CAVER is a software tool for analysis and visualization of tunnels and channels in protein structures. Tunnels are void pathways leading from a cavity buried in a protein core to the surrounding solvent. Unlike tunnels, channels lead through the protein structure and their both endings are opened to the surrounding solvent. Studying of these pathways is highly important for drug design and molecular enzymology.

CAVER Analyst

CAVER provides rapid, accurate and fully automated calculation of tunnels and channels in static and dynamic structures. The molecules amendable to analysis of CAVER include proteins, nucleic acids, or inorganic materials.

The software is available as CAVER 3.0 command-line version, CAVER 3.0 PyMol plugin or graphical application CAVER Analyst 1.0. The latest version of CAVER enables the analysis of molecular dynamics simulations. CAVER Analyst allows easy set-up of calculation, visualization of results, and efficient visual analysis of data.



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765 citations
6071 registered users
111396x CAVER downloaded

news

January 8, 2019

CAVER was cited in the NATURE journal in article Cryo-EM structure of the human α1β3γ2 GABAA...

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CAVER was cited in the NATURE Communications journal in article Cryo-EM structures of KdpFABC...

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January 8, 2019

CAVER was cited in the Proceedings of the National Academy of Sciences journal in article...

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