@article{1082672, author = {Biedermannová, Lada and Prokop, Zbyněk and Gora, Artur Wiktor and Chovancová, Eva and Kovács, Mihály and Damborský, Jiří and Wade, Rebecca C.}, article_location = {USA}, article_number = {34}, doi = {http://dx.doi.org/10.1074/jbc.M112.377853}, keywords = {HLD; haloalkane dehalogenase; MD; molecular dynamics; RAMD; random acceleration molecular dynamics; ABF; adaptive biasing force; RC; reaction coordinate; FEP; free energy perturbation; NATA; N-acetyltryptophan amide}, language = {eng}, issn = {0021-9258}, journal = {The Journal of Biological Chemistry}, title = {A Single Mutation in a Tunnel to the Active Site Changes the Mechanism and Kinetics of Product Release in Haloalkane Dehalogenase LinB}, volume = {287}, year = {2012} }