@ARTICLE{10.3389/fchem.2018.00650,  
AUTHOR={Marques, Sérgio M. and Bednar, David and Damborsky, Jiri},   
TITLE={Computational Study of Protein-Ligand Unbinding for Enzyme Engineering},      
JOURNAL={Frontiers in Chemistry},      
VOLUME={6},      
PAGES={650},     
YEAR={2019},      
URL={https://www.frontiersin.org/article/10.3389/fchem.2018.00650},       	
DOI={10.3389/fchem.2018.00650},      	
ISSN={2296-2646}
}